Vesna Eterovic

Distinguished Research Professor
Ph.D. 1971, National Uni. of Cordoba, Argentina

Academic Department(s)
Department of Biochemistry

Research Area
Neuroscience-Nicotinic acetylcholine receptor

Research Interest
The mechanism of how cembranoids block the muscle type acetylcholine receptor, with the purpose of contributing to a better understanding of the structure and function of this important prototype of all ligand-gated ion channels.

Selected Publications
4R-cembranoid protects against diisopropylfluorophosphate-mediated neurodegeneration.  Ferchmin PA, Andino M, Reyes-Salaman R, Alves J, Vélez-Roman J, Cuadrado B, Carrasco M, Torres-Rivera W, Segarra A, Martins AH, Lee JE, Eterovic VA.  Neurotoxicology. 2014 Jun 10;44C:80-90.
Kinin-B2 receptor exerted neuroprotection after diisopropylfluorophosphate-induced neuronal damage. Torres-Rivera W, Perez D, Park KY, Carrasco M, Platt MO, Eterovic VA, Ferchmin PA, Ulrich H, Martins AH.   Neuroscience, 2013 Sept 5;247:273-9. 
Protective activity of (1S, 2E, 4R,6R, 7E, 11E)-2,7,11-cebratriene-4,6-diol analogues against diisopropylfluorophosphate neurotoxicity: Preliminary structure-activity relationship and pharmacophore modeling. Eterovic VA, Del Valle-Rodríguez A, Perez D, Carrasco M, Khanfar MA, El Sayed KA, Ferchmin PA.   Bioorganic & Medicinal Chemistry, 2013 Aug 1;21(15):4678-86. 
γ-Aminobutyric acid type a receptor inhibition triggers a nicotinic neuroprotective mechanism. Ferchmin PA, Pérez D, Castro Alvarez W, Penzo MA, Maldonado HM, Eterovic VA. J Neurosci Res. 2013 Mar;91(3):416-25.

Acute neuronal injury and blood genomic profiles in a nonhuman primate model for ischemic stroke. Rodriguez-Mercado R, Ford GD, Xu Z, Kraiselburd EN, Martinez MI, Eterović VA, Colon E, Rodriguez IV, Portilla P, Ferchmin PA, Gierbolini L, Rodriguez-Carrasquillo M, Powell MD, Pulliam JV, McCraw CO, Gates A, Ford BD. Comp Med. 2012 Oct;62(5):427-38.

Contact Information
Universidad Central del Caribe
P.O. Box 60327
Bayamón, PR 00960-6032

Tel  (787) 798-3001 ext. 2032