The Center unifies a multi-institutional group of researchers focused on glial cell investigation and oriented to disorders originated by or related to glial cell function and pathology. The center represents scientific research groups from UCC and adjunct members from UPR. At UCC there is a large group of researchers from the basic sciences departments who share interrelated research interests in neuroglial cell physiology, molecular biology, biochemistry, pharmacology and biophysics. Glial cells (the “silent brain”) do not generate spikes. Instead, glial signaling in brain is through molecular and ionic mechanisms inside of the glial syncitium and between glia and neurons. These signaling avenues use a wide variety of molecules which can be detected with the help of new techniques developed or employed by the investigators. In addition, the Center uses common core facilities, such as the Common Instrumentation Area, the Optical Imaging Facility and the Behavioral Testing Facility which provide services to Center members. The Center is led by the Director (Dr. Skatchkov, Distinguished Research Professor of Physiology and Biochemistry) who is assisted by an Associate Scientific Director (Dr. Eaton, Professor of Biochemistry). The Center has established wide-spread national and international partnerships. The Center coordinates lab meetings, journal clubs, seminars, and an Annual Symposium “CaribeGLIA” which is attend by distinguished national and international glial researchers, physicians, students and associates. NOTE: The Annual Symposium is on hold until after the pandemic.