Legier Rojas

Ph.D. 1987, University of Puerto Rico

Academic Department(s)
Department of Physiology

Research Area

Research Interest
Understand the mechanism by which thyroids hormones induces non-genomic action in the pre- and post-synaptic region in a developmental tissue.
The effects of cholesterol and lipid exposed mutations on the Torpedo and muscle- type AChR channel function.

Selected Publications
Quinine enhances the behavioral stimulant effect of cocaine in mice.  Huertas A, Wessinger WD, Kucheryavykh YV, Sanabria P, Eaton MJ, Skatchkov SN, Rojas LV, Maldonado-Martinez G, Inyushin M.  Pharmacol Biochem Behav. 2014 Dec 4. S0091-3057(14)00321-9.
L-DOPA Uptake in Astrocytic Endfeet Enwrapping Blood Vessels in Rat Brain. Inyushin MY, Huertas A, Kucheryavykh YV, Kucheryavykh LY, Tsydzik V, Sanabria P, Eaton MJ, Skatchkov SN, Rojas LV, Wessinger WD. Parkinsons Dis. 2012;2012:321406.

Triiodothyronine (T3) action on aquatic locomotor behavior during metamorphosis of the bullfrog Rana catesbeiana. Fernández-Mongil M, Venza CJ, Rivera A, Lasalde-Dominicci JA, Burggren W, Rojas LV. Int J Dev Biol. 2009;53(1):101-8.

Thyroid-stimulating hormone and follicle-stimulating hormone status in Hispanic women during the menopause transition. Rojas LV, Nieves K, Suarez E, Ortiz AP, Rivera A, Romaguera J. Ethn Dis. 2008 Spring;18(2 Suppl 2):S2-230-4.

The polarity of lipid-exposed residues contributes to the functional differences between Torpedo and muscle-type nicotinic receptors. Guzmán GR, Ortiz-Acevedo A, Ricardo A, Rojas LV, Lasalde-Dominicci JA. J Membr Biol. 2006;214(3):131-8.

Novel beta subunit mutation causes a slow-channel syndrome by enhancing activation and decreasing the rate of agonist dissociation. Navedo MF, Lasalde-Dominicci JA, Báez-Pagán CA, Díaz-Pérez L, Rojas LV, Maselli RA, Staub J, Schott K, Zayas R, Gomez CM. Mol Cell Neurosci. 2006 May-Jun;32(1-2):82-90.
Contact Information
Universidad Central del Caribe
P.O. Box 60327
Bayamón, PR 00960-6032
Tel  (787) 798-3001 ext. 2302 and 2056
e-mail: lrojas@uccaribe.edu