Misty Eaton

Professor
Ph.D. 1990, Uni. Texas Southwestern Medical School

Academic Department(s)
Department of Biochemistry

Research Area
Functional Role of Potassium Channels in Astrocytes

Research Interest
Astrocytic potassium channels and epilepsy
Astrocytic potassium channels and ischemia
Astrocytic potassium channels and diabetes

Selected Publications
Kainate-induced calcium overload of cortical neurons in vitro: Dependence on expression of AMPAR GluA2-subunit and down-regulation by subnanomolar ouabain. Abushik PA, Sibarov DA, Eaton MJ, Skatchkov SN, Antonov SM.  Cell Calcium. 2013 May 28

Molecular mechanisms of EAST/SeSAME syndrome mutations in Kir41 (KCNJ10). Sala-Rabanal M, Kucheryavykh LY, Skatchkov SN, Eaton MJ, Nichols CG. J Biol Chem. 2010 Nov 12;285(46):36040-8. 
 
Potassium channel activity and glutamate uptake are impaired in astrocytes of seizure-susceptible DBA/2 mice. Inyushin M, Kucheryavykh LY, Kucheryavykh YV, Nichols CG, Buono RJ, Ferraro TN, Skatchkov SN, Eaton MJ. Epilepsia. 2010 Sep;51(9):1707-13. 
 
Ischemia Increases TREK-2 Channel Expression in Astrocytes: Relevance to Glutamate Clearance. Kucheryavykh LY, Kucheryavykh YV, Inyushin M, Shuba YM, Sanabria P, Cubano LA, Skatchkov SN, Eaton MJ. Open Neurosci J. 2009 Jan 1;3:40-47. 
 
Downregulation of Kir41 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes.  Kucheryavykh YV, Kucheryavykh LY, Nichols CG, Maldonado HM, Baksi K, Reichenbach A, Skatchkov SN, Eaton MJ.  Glia. 2007 Feb;55(3):274-81. 
 

IBRO GLIA Workshop 2013

 
Contact Information
Universidad Central del Caribe
P.O. Box 60327
Bayamón, PR 00960-6032

Tel  (787) 798-3001 ext. 2034
e-mail misty.eaton@uccaribe.edu
mistyeaton1960@yahoo.com