Ramon Jorquera

Assistant Professor
Ph.D., 2007, Austral University of Chile
ORCID #0000-0002-5460-1755

Academic Department(s)

Research Area
Ion Channels
Synaptic Transmission
Vesicle Trafficking

Research Interest
Neural Computation, Short-Term Plasticity, Synaptic Memory, Nerve and Muscle Excitability, Vesicle Fusion, Neuro-Developments, Non-Classical Synapses, Animal Behavior, General Physiology and Biophysics.

Dr. Jorquera is working to determine the role of Complexin in synaptic vesicle trafficking and in short-term plasticity using electrophysiology, imaging, behavior and genetic manipulation of Drosophila. Complexin binds the SNARE complex for vesicle fusion. In model systems, the absence of Complexin dramatically increase the spontaneous vesicle fusion and at the same time diminishes the evoked fusion induced by calcium. Complexin controls the expression of glutamate receptors during long term potentiation but its role in the post synaptic compartment remains to be elucidated. Students will use fluorescent dyes to monitor intracellular Ca2+ and elucidate how the spontaneous release in Complexin regulates excitability.


Contact Information
Universidad Central del Caribe
P.O. Box 60327
Bayamón, PR 00960-6032

Tel.: 798-3001 x2166
e-mail: ramon.jorquera@uccaribe.edu