RCMI Publications




  1. Banerjee, A., Martínez, J.A., Longas, M.O., Zhang, Z., Santiago, J., Baksi, K., and Banerjee, D.K. N-Acetylglucosaminyl 1-Phosphate Transferase: An Excellent Target for Developing New Generation Breast Cancer Therapeutic.  Adv Exptl Med Biol. 842:355-374 (2015). PMID: 25408354  PMCID:  In Progress. 
  1. Berríos, V., Boukli, N., Rodríguez, J.W., Negraes, P., Schwindt, T., Trujilli, C., Cubano, L., Ulrich, H., Ferchmin, P., Eterovic, V., Martins, A. Paraoxon Interfere with Correct Neural Stem Cell Differentiation.  Neurochemistry Research (2015) (Published Online) DOI 10.1007/s11064-015-1548-7.   PMID: 25758980  PMCID:* 
  1. Humpries-Bickley, T, Castillo-Pichardo, L, Corujo-Carro, F, Duconge, J, Hernández, E, Vlaar, C, Rodríguez-Orengo, JF, Cubano, LA, and Dharmawardhane, S. Pharmacokinetics of rac inhibitor Ehop-016 in Mice by Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci, 2015, 981-982C:19-26. (2015) PMID: 25594952 PMCID: 4306626 Available on 2016/2/15 
  1. Martínez, O., Miranda, E., Ramírez, M., Santos, S., Vázquez, L., Rivera C., Sánchez, T., Ríos-Olivares, E., Otero, M. Immunomodulator-Based Enhancement of Anti-Smallpox Immune Responses.  PLoS One. 13;10(4):e0123113. (2015) PMID: 25875833  PMCID: 4395221* 
  1. Martins, A H, Hu, Jing, Xu, Zhenfeng, Mu, Chaofeng, Alvarez, P., Byron F., El Sayed, K., Eterovic, V., Ferchmin, P., Hao, J. Neuroprotective Activity of (1S,2E,4R,6R,-7E,11E)-2,7,11-Cembratriene-4,6-diol (4R) In Vitro and in Vivo in Rodent Models of Brain Ischemia.  Neuroscience, S0306-4522(15)00143-8.  (2015) PMID: 25677097  PMCID: 4369428 * Available on 2016/4/16 
  1. Otero, M., Zayas, B., Miranda, E., Vélez C., Hernández, W., Cox, O. Immunomodulatory Response Triggered by the Alkaloids, 3-amino-7-benzylbenzimidazo[3,2-a]Quinolinium Chloride (ABQ-48) and 3-nitro-7-benzybenzylbenzimidazo[3,2-a] Quinolinium Chloride (NBQ-48).  J Cancer Res Therap Oncol 1:1-6 (2015). *   
  1. Rivera-Pagán, A.F., Rivera-Aponte, D.E., Melnik-Martínez, K.V., Zayas-Santiago, A. Kucheryavykh, L.Y., Martins, A.H., Cubano, L.A., Skatchkov, S.N. and Eaton, M.J. Up-regulation of TREK-2 potassium channels in cultured astrocytes requires De Novo protein synthesis: Relevance to localization of TREK-2 channels in astrocytes after transient cerebral ischemia. PLOS 10(4):e0125195 (2015). PMID: 25886567  PMCID: 4401746.* 
  1. Sanabria, R., Rivera-Torres Y., Rosario, J., Ríos, C., Gutiérrez, R., Carballeira, N., Vélez, C., Zayas, B., Álvarez, F., Ortiz, G., Serrano, V., Altieri, J., Ríos-Olivares, E., Rodríguez, J.W. Synthesis of Novel C5-Curcuminoid-Fatty Acid Conjugates and Mechanistic Investigation of their Anticancer Activity.  BMCL-D-15-00284R1. 15;25(10):2174-80 (2015) PMID: 25881826  PMCID:  * 
  1. Vélez-Carrasco W, Green, CE, Catz P, Furimsky A, O’Loughlin K, Ferchmin PA, and Eterovic VA. Pharmacokinetics and metabolism of 4R-cembranoid.  PloS One 26:10(3):e0121540. (2015) PMID: 25811857  PMCID: 4374761. 
  1. Yehia, B., Robeiro, P., Althoff, K., Agwu, A., Horberg, M., Samji, H., Gebo, K. Impact of Age on Retention in Care and Viral Suppression. Journal of Acquired Immune Deficiency Syndromes.  68(4):413-419.  (Collaboration Efforts of RRC)  PMID: 25559604  PMCID: 43344738 * 
  1. Skatchkov, S., Bukauskas, F., Benedikt, J., Inyushin, M., Kucheryavykh, Y. Intracellular Spermine Prevents Acid induced Uncoupling of Cx43 Gap Junction Channels. NeuroReport (2015) (In Press).*



  1. Abraham, A., Althoff, K., Jing, Y., Jing, Y., Estrella, M., Kitahata, M., Wester, W., Bosch, R., Crane, H., Eron, J., Gill, M., Horgerg, M., Justice, A., Klein, M., Krishnasami, Z., Mayor, A., Moore, R., Palella, R., Parikh, C., Silverberg, M., Golub, E., Jacobson, L., McKaig, R., Napravnik, S., Rodríguez, B., Lucas, G. End Stage Renal Disease among HIV-Infected Adults in North America.  Clinical Infectious Diseases. pii: ciu919.  Epub (2014) PubMed (2015) PMID: 25409471  PMCID: 4357817  (Collaboration Efforts of RRC) * Available on 2016/3/15
  1. Althoff, K., Rebeiro, P., Brooks, J., Buchacz, K., Gebo, K., Martin, J., Horberg, M. Disparities in the Quality of HIV Care when using US Department of Health and Human Services Indicators.  Clinical of Infectious Diseases, 58(8):1185-1189. (2014) PMID: 24463281  PMCID: 3967825  (Collaboration Efforts of RRC) *
  1. Beacheler, D., Abraham, A., Silverberg, M., Jing, Y. Fakhry, C., Gill, M.J., Dubrow, R., Kitabata, M, Klein, M.B., Burchell, A.N., Korthuis, P.T., Moore,R.D., D’Souza, G.,  Incidence and Risk Factors of HPS-Related and HPV-Unrelated Head and Neck Squamous Cell Carcinoma in HIV-Infected Individuals.  Oral Oncol. S1368-8375(14)00272-3 (2014).  PMID: 25301563  PMCID:4253676   (Collaboration Efforts of RRC) (Mayor, A.-Co-author)*
  1. Castillo-Pichardo, L, Dharmawardhane, S, and Rodríguez-Orengo, JF. Rapid Quantification of Resveratrol in Mouse Plasma by Ultra High Pressure Liquid Chromatography (UPLC) Coupled to Tandem Mass Spectrometry. PR health Sci J.  33(4):151-56. (2014) PMID: 25563031  PMCID: .
  1. Castillo-Pichardo, L., Humphries, T., De la Parra, C., Forestier, I., Martínez, M., Hernández, E., Vlaar, C., Ferrer, Y., Washington, A., Cubano, L., Rodríguez, J., Dharmawardhane, S. The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model.  Transl oncol 24;7(5):546-55. PMID: 25389450  PMCID:4225654*
  1. El-Hage, N., Rodríguez, M., Podhaizer, E., Zou, S., Dever, S., Snider, S., Knapp, P., Breardsley, P., Hauser, K. The Phosphodiesterase Inhibitor, Ibudilast (AV411), and its AV1013 Analogue, Reduce HIV-1 Replication and Neuronal Death Induced by HIV-1, and morphine.  AIDS 19:28(10):1409-19(2014) PMID: 24732776  PMCID: 4300098 (Retro)
  1. Esponda, O.L., Hunter, R., Río, J.R., Washington, A.V. Levels of Soluble TREM-Like Transcript 1 in Patients Presenting to the Emergency Department with Chest Pain.  Clin Appl Thromb Hemost.  pii: 1076029614547298.  Epub (2014) PubMed (2015).  PMID: 25147325  PMCID: 4356632
  1. Ferchmin, P., Andino, M., Salamán, R., Alves, J., Vélez, J., Cuadrado, B., Carrasco, M., Torres, W., Segarra, A., Martins, H., Leec, J., Eterovic, V.   4R-Cembranoid Protects Against Diisopropylfluorophosphate-Mediated neurodegeneration.    (2014) PMID: 24928201  PMCID:4176603*
  1. Fitting, S., Zou, S., El-Hage, N., Suzuki, M., Paris, J.J., Schier, C.J., Rodríguez, J.W., rodríguez, M., Knapp, P.E., Hauser, K.F.  Opiate Addiction Therapies and HIV-1 Tat:  Interactive Effects on Glial [Ca2+]I, Oxyradical and Neuroinflammatory Chemokine Production and Correlative Neurotoxicity.  HIV Res. 12(6):424-434 (2014) PMID: 25760046  PMCID:
  1. Font, I., Castro, L., Nieves, M., Maldonado, M., Mayor, A., Vilá, L. Factors Associated with Regional Rheumatic Pain Syndrome in a Population of Puerto Rican with Diabetes Mellitus.  Clinical Rheumatology 33(7):995-1000.  (2014).  PMID: 24522480  PMCID: 4302737.
  1. Huertas, A., Wessinger, W., Kucheryavykh, Y., Sanabria, P., Eaton, M., Skatchkov, S., Rojas, L., Maldonado, G., Inyushin, M. Quinine Enhances the Behavioral Stimulant Effect of Cocaine in Mice. Pharmacology, Biochemistry and Behavior. Dec 5;129C:26-33. Epub (2014) PubMed (2015).  NIHMSID: 649378.  PMID:25482328  PMCID: 4356011 *
  1. Humpries-Bickley, T, Castillo-Pichardo, L, Corujo-Carro, F, Duconge, J, Hernández, E, Vlaar, C, Rodríguez-Orengo, JF, Cubano, LA, and Dharmawardhane, S. Pharmacokinetics of rac inhibitor Ehop-016 in Mice by Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci, 2015, 981-982C:19-26. (2015) PMID: 25594952 PMCID: 4306626 Available on 2016/2/15
  1. Kucheryavykh, L., Rolón-Reyes, K., Kucheryavykh, Y., Skatchkov, S., Eaton, M., Sanabria, P., Wessinger, W., Inyushin, M. Glioblastoma Development in Mouse Brain: General Reduction of OCTs and Mislocalization of OCT3 Transporter and Subsequent Uptake of ASP+ Substrate to the Nuclei. J. Neurosci. Neuroeng. 3, 3-9 (2014). PMID: 25165637 PMCID: 4143131 NIHMSID: 610395.*
  1. Ortiz, A.P., Reyes, J.C., Palefsky, J., Negrón, J., Da Costa, M., Vázquez, M., Rivera, A.I., Matos, T.D., Ríos-Olivares, E., Tortolero, G. Oral Human Papillomavirus Infection amon Drug Users in Puerto Rico.  PR Health Sci J. 33(4):190-196 (2014).  PMID: 25563037  PMCID: *
  1. Ramos, G., Loperena, y., Ortiz, G., Reyes, F., Szeto, A., Vera, J., Vélez, J., Morales, J., Morrero, D., Castillo-Pichardo, L., Dharmawardhane, S., Meléndez, E., Washington, V. The Addition of a Pregnenolone Pendant Group Enhances the Anticancer Properties of Titanocene Dichloride in a mcf-7 Xenograft Model.  Anticancer Res. 34(4):1609-15 (2014) PMID: 24692689  PMCID: 4053690.*
  1. Rebeiro, P., Horberg, M., Gange, S., Gebo, K., Yehia, B., Brooks, J., Althoff, K. Strong Agreement of Nationally Recommended Retention Measures from the Institute of Medicine and Department of Health and Human Services. PLosOne, 9(11:e111772. (2014).  ) PMID: 25375099  PMCID: 4357817  (Collaboration Efforts of RRC) *
  1. Ríos. G., Estrada, M., Mayor, A.M., Vila, L.M. Factors associated with tender points count in Puerto Ricans with fibromyalgia syndrome.  PR Health Sci J. Sept;33(3);112-6. (2014).  PMID: 25244879  PMCID: 4222946 *.
  1. Sanabria, D.J., Rivera, Y., Maldonado, G., Domínguez, I., Ríos, C., Díaz, D., Rodríguez, J.W., Altieri, J., Ríos-Olivares, E., Cintrón, G., Montano, N., Caballeira, N. Antibacterial Activity of 2-Alkynoic Fatty Acids against Multidrug-Resistant Bacteria.  Phys. Lipids.  178: 84-91.  (2014)  PMID: 24365283  PMCID: 4048129*
  1. Santiago, E., Mayor, A., Fernández, D., Ruiz, Y., Hunter, R. Anemia in a Cohort of HIV-Infected Hispanics:  Prevalence, Associated Factors and Impact on one Year Mortality.  BMC Research Notes. 8;7:439 (2014).  PMID: 25005803  PMCID: 4099091*
  1. Schikorski, T. Readily Releasable Vesicles Recycle at the Active Zone of Hippocampal Synapses.  Proc Natl Acad Sci U SA. 111(14):5415-20.  (2014)  PMID: 24706824  PMCID:3986142 *
  1. Skatchkov, S., Woodbury, M., and Eaton, M. (in press invited review) The Role of Glia in Stress: Polyamines and Brain Disorders. Psychiatric Clinics of North America 2014 Dec;37(4):653-678. 2014) PMID: 25455070  PMCID: 4394863 * Available on 2015/12/1
  1. Velásquez-Martínez MC, Vázquez-Torres R, Rojas LV, Sanabria P, Jiménez-Rivera CA. Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons.  2014 Sep 28. pii: S0028-3908(14)00308-6. doi: 0.1016/j.neuropharm.2014.09.002. PMID:25261018 PMCID:4252518 [Available on 2016/1/1]
  1. Yehia, B.R., Rebeiro, P., Althoff, K.N., Agwu, A.L., Horberg, M.A., Samji, H., Napravnik, S., Mayer, K., Tedaldi, E., Silverberg, M.J., Thorne, J.E., Burchell, A,N., Rourke, S.B., Rachlis, A., Mayor, A., Gill, M.J., Zinski, A., Ohl, M., Anastos, K., Abraham, A.G., Kitahata, M.M., Moore, R.D., and Gebo, K.A. The Impact of Age on Retention in Care and Viral Suppression. JAIDS.  (2014) [Epub ahead of print].  PMID: 25559604  PMCID: 4334738 *
  1. Zayas, A., Agte, S., Rivera, Y., Benedikt, J., Ulbricht, E., Karl, A., Dávila, J., Savvinov, A., Kucheryavykh, Y., Inyushin, M., Cubano, L., Pannicke, T., Ve. R., Francke M., Verkhratsky, A., Eaton, M., Reichenbach, A., Skatchkov, S. Unidirectional Photoreceptor-to-Muller Glia Coupling and Unique K+ Channel Expression in Caiman Retina.  PLOS One (2014).  PMID: 24831221  PMCID:4022631*
  1. Zueva, L, Makarov, V., Zayas-Santiago, A., Golubeva, T., Korneeva,E., Savvinov, A., Eaton, M., Skatchkov, S., Inushin, M. Müller Cell Alignment in Bird Fovea:  Possible role in Vision.  J Neurosci Neuroeng. 1:3(2):85-91.  PMID: 25866702 PMCID:389649 *
  1. Zueva L, Rivera Y, Kucheryavykh L, Skatchkov S, Eaton M, Sanabria P, Inyushin M, Electron Microscopy in Rat Brain Slices Reveals Rapid Accumulation of Cisplatin on Ribosomes and other Cellular Components only in Glia. Res.Pract. (2014) 174039.  PMID: 25610648  PMCID:4291194*
  1. Tossas K, Hunter R., Mayor A.M., Fernández D., Dworkin, M. Late Testing for Human Immunodeficiency virus in a Puerto Rican Cohort. (2014) (In Press).



  1. Abushik, P.A., Sibarov, D.A., Eaton, M.J., Skatchkov, S.N. and Antonov, S.M. Kainate-Induced Calcium Overload of Cortical Neurons in Vitro: Dependence on Expression of AMPAR GluA2-Subunit and Down-Regulation by Subnanomolar Ouabain. Cell Calcium. 54:95-104. (2013). PMID: 23721822  PMCID: 3723740*
  1. Buhl, L., Jorquera, R., Akbergenova, Y., Huntwork, S., volfson, D., Littleton, J. Differential Regulation of Evoked and Spontaneous Neurotransmitter Release by C-Terminal Modifications of Complexin.  Mol Cell Neurosci.  52:161-72 (2013).  PMID: 23159779.  PMCID: 3540146.
  1. Bykhovskaia, M., Jagota, A., González, A., Vasin, A., Littleton, J. Interaction of the Complexin Accessory hélix with the C-Terminus of the SNARE Complex:  molecular-Dynamics Model of the Fusion Clamp.  Biophys J., 105(3):679-90.  (2013).  PMID: 23931316.  PMCID: 3736676.
  1. Castillo-Pichardo, L., Cubano, L., Dharmawardhane, S. Die Grape Polyphenol Resveratrol Increases mammary Tumor Growth and Metastasis in Immunocompromised Mice.  BMC Complement Altern Med.  8:13:6. (2013) PMID: 23298290.  PMCID: 3544562.*


  1. Dworkin, M., Peterson, C., Gao, W., Mayor, A., Hunter, R., Negrón, E., Fleury, A., Besch, C. Efficacy of a Food Safety Comic Book on Knowledge and Self-Reported Behavior for persons Living with AIDS.  PloS One 4;8(10)E72874. (2013) PMID: 24124447.  PMCID: 3790879.
  1. Dworkin, M., Peterson, C., Gao, W., Mayor, A., Hunter, R., Negrón, E., Fleury, A., Besch, C. Food Safety Knowledge, Belief and Behavior of Persons with AIDS:  A Multicenter Study.  Food Prot. Trends, 33(1):32-41.  (2013) PMID: 25061438.  PMCID: 4106445.  NIHMSID:  NIHMS:485956*
  1. Eterovic, V., Del, Valle, A., Pérez, D., El Sayed, K., Ferchmin, P. Protective Activity of (15, 2E, 4R, 6R., 7E., 11E)—2,7,11-Cembratriene -4,6- Diol Analogues Against Diisopropylfluorosphosphate Neurotoxicity.  Bioorganic Medicinal Chem.  1;21(15):4678-86  (2013). PMID: 23769165.  PMCID: 3892699 *
  1. Fanchaou M, Cubano L, Maldonado H, Bychkov R. PKC Independent Inhibition of Voltage Gated Calcium Channels by Volatile Anesthetics in Freshly Isolated Vascular Myocytes from the Aorta.  Cell Calcium.  2013 Oct;54(4):257-65 (2013). PMID: 23948226.  PMCID: 3788677
  1. Feliciano, P., Andrade, R., Bykhovskaia, M. Synapsin II and Rab3a Cooperate in the Regulation of Epileptic and Synaptic Activity in the CA1 Region of the Hippocampus.  J Neurosci. 33:183-30 (2013) PMID: 24227741 PMCID: 3893359.
  1. Ferchmin, P, Pérez, D., Castro, W., Penzo, M., Maldonado, H., Eterovic, V. y-Aminobutyric Acid Type a Receptor Inhibition Triggers a Nicotinic Neuroprotective Mechanism.  Neurosci. Res., 91(3):416-25 doi:10.1002/jnr.23155 (2013). PMID: 23280428  PMCID: 4122130 *
  1. Hanna, D., Buchacz, K., Gebo, K. North American AIDS Cohort Collaboration on Research and Design in antiretroviral Therapy Initiation and Virologic Suppression among Newly Treatment-Eligible HIV-Infected Individuals in North America 2001-2009.  Clin Infect Dis.  56(8):1174-82 (2013) Collaborators:  Hunter, R., Mayor, A. PMID: 23315317 PMCID: 3657490*
  1. Hayoz S, Cubano L, Maldonado H, Bychkov R. Protein Kinase A and C Regulate Leak Potassium Currents in Freshly Isolated Vascular Myocytes from the Aorta.  PLoS One. 2013 Sep 23;8(9):e75077. (2013) PMID: 24086441 PMCID: 3781042.
  1. Inyushin, M., Arencibia, F., De la Cruz, A., Vázquez, R., Colón, K., Sanabria, P., Jiménez, C. New Method to Visualize Neurons with DAT in Slices of Rat VTA using Fluorescent Substrate for DAT, ASP+.  J Neurosci Neuroeng. 2:98-103 (2013) PMID: 24052926 PMCID: 3773718.*
  1. Inyusin, M., Sibarov, D., Volnova, A. Comparative Analysis of Changes in Membrane Currents in Neurons and Astrocytes in Rat Hippocampal Slices after Stimulation of Glutamatergic Transmission.  Dokl Biol Sci.  449:65-7 (2013) PMID: 23652428  PMCID:  “Not Applied” (Russian Language)*
  1. Makarov V., Kucheryavykh L., Kucheryavykh Y., Rivera A., Eaton M., Skatchkov S., Inyushin Transport Reversal During Hetero-exchange: a Kinetic Study. Journal of Biophysics 2013:683256 (2013) PMID: 24307897 PMCID: 3825127.*
  1. Maldonado, C., Alicea, D., González, M., Bykhovskaia, M., Marie, B. Adar is Essential for Optimal Presynaptic Function.  Mol Cell Neurosci. 52:173-80. (2013) PMID: 23127996 PMCID: 3613243
  1. Maldonado, G., Fernández, D., Ríos-Olivares, E., Hunter, R. HIV/AIDS in the Elderly:  Immunological Changes Between Gender with Body Mass Index.  Jornal of Health Care for the Poor and Underserved.  Health Care Poor Underserved 24(4 Suppl):94-105. (2013) PMID: 24241264  PMCID: 4041281NIHMSID: 590815*
  1. Mayor, A., Fernández, D., Colón, H., Thomas, J., Miranda, C., Hunter,R. Hepatitis C HIV Multimedia Prevention in Poor Hispanic HIV Infected Injecting Drug Users:  Six Months after Intervention.  Journal of Health Care for the Poor and Underserved.  J Health Care Poor Underserved 24(4 Suppl):29-37. (2013).  PMID: 24241258 PMCID: 4071764 Available on 11/1/2014 *
  1. Miranda, M., Suárez, E., Abbas, M., Tosado, C., Mejías, R., Boukli, N. HLA Class I & II Alleles in Multiple Sclerosis Patients from Puerto Rico.  Boletín Asoc Med PR.  Vol 105 (1). (2013).  PMID: 23767380 PMCID:
  1. Nieves-Plaza, M., Castro, L., Font, Y., Mayor, A., Vilá, L. Association of Hand or Knee Osteoarthritis with Diabetes Mellitus in a Population of Hispanics from Puerto Rico.  J of Clin Rheumatology.  19(1):1-6. doi:  1097/RHU.0b013e31827cd578.  PMID: 23319016 PMCID: 3815459.*
  1. Ruiz, Y., Miranda, C., Hunter, R.. K-RAS Mutation Profile in Puerto Rican Patients with Colorectal Cancer:  Trends in Expression of K-RAS Mutation in PR since April 2009 to January 2011.  The International Journal of Biological Markers. doi: 10.5301/JBM.5000043  (2013) PMID: 23999847 PMCID: 4042672.*
  1. Sala-Rabanal, M., Li, D., Dake, G., Kurata, H., Inyushin, M., Skatchkov, S., Nichols, C. Polyamine Transport by the Polyspecific Organic Cation Transporters OCT1, OCT2 and OCT3.  Molecular Pharmaceutics.  1;10(4):1450-8.  doi: 10.1021/mp400024d.R1 (2013) PMID: 23458604.  PMCID: 3632321  NIHMSID: 457726. *
  2. Santiago, Y., González, T., Castro, L., Ríos, G., Martínez, D., Rodríguez, V., González, R., Mayor, A., Vilá, L. Impact of managed Care Health Insurance System for Indigent Patients with Rheumatoid Arthritis in Puerto Rico.  Clinical Rheumatology.  doi: 1007/s10067-013-2167-9.  (2013) PMID: 23314687.  PMCID: 3780563.*
  1. Suárez-Arroyo, I., Rosario-Acevedo, R., Aguilar-Pérez, A., Clemente, P., Cubano, L., Shneider, R., Martínez-Montemayor, M. Anti-Tumor Effects of Ganoderma Lucidum (Reishi) in Inflammatory Breast Cancer in In Vivo and In Vitro Models.  PLoS ONE.  8(2): e57431. doi:10.1371/journal.pone.0057431. (2013)  PMID: 23468988.  PMCID: 3585368*
  1. Thompson, K., Ríos-Olivares, E. Making a Difference:  Steps to Develop a Research Pipeline in Puerto Rico.  J Health Care Poor Underserved.  24(4 0):4-7.  (2013)  PMID: 24241255.  PMCID: 4096687
  1. Torres, W., Pérez, D., Park, K., Carrasco, M., Platt, M., Eterovic, V., Ferchmin, P., Ulrich, H., Martins, A. Kinin-B2 Receptor Exerted Neuroprotection after Diisopropylfluorophosphate-Induced Neuronal Damage.  2:247C:273-279 (2013).  PMID: 23735753 PMCID: 3740336
  1. Yang, J., Hu, D., Xia, J., Liu, J., Zhang, G., Gendelman, H., Boukli, N., Xiong, H. Enhancement of NMDA Receptor-Mediated Excitatory Postsynaptic Currents by gp120-Treated Macrophages:  Implications for HIV-1 –associated Neuropathology.  Journal of Neuroimmune Pharmacology. 8(4):921-33.  (2013). PMID: 23660833 PMCID: 3740075*



  1. Benedikt, J., Inyushin, M., Kucheryavykh, Y., Rivera, Y., Kucheryavykh, L, Nichols, C., Eaton, M., Skatchkov, S. Intracellular Polyamines enhance Astrocytic Coupling.    23:1021-1025. Doi: 10.1097/WNR.0b013e32835aa04b. PMID: 23076119.  PMCID: 3658138 *
  1. Bychkov, R., Cubano, L., Hayoz, S., Maldonado, H. Interplay Between Gap Junctions and K2p Channels; The Switch from PDBY Elicited Contraction to the Dilation of the Thoracic Aorta.  FASEB J. 26:870-75. (2012) (Abstract).
  1. Boukli, N., Shetty, V., Cubano, L., Ricaurte, M., Coelho-dos-Reis, J., Nickens, Z., Shan, P., Talal, A., Philip, R., Jain, P. Unique and Differential Protein Signatures within the Mononuclear Cells of HIV-1 and HCV mono-Infected and co-Infected Patients.  Clinical Proteomics 9:11 (2012). Doi:10.1186/1559-0275-9-11. PMID: 22958358.  PMCID: 3582525 *
  1. Castillo-Pichardo, L., Dharmawardhane, S. Grape Polyphenols Inhibit Akt/Mammalian Target of Rapamycin Signaling and Potentiate the Effects of Gefitinib in Breast Cancer.  Nutrition and Cancer. 64(7):1058-69. (2012). PMID23061908. *
  1. De la Parra, C., Otero, E., Martínez-Montemayor, M., Dharmawardhane, S. The Soy Isoflavone Equol may Increase Cancer Malignancy via Upregulation of Eukaryotic Protein Synthesis Initiation Factor elF4G.  Biol. Chem. (50):41640-50. (2012) PMID: 23095751.  PMCID: 3516715.*
  1. Derive, M., Bouazza, Y., Sennoun N., Marchionni, S., Quigley, L., Washington,V., Massin, F., Max, J., Ford, J., Alauzet, C., Levy, B., McVicar, D., Gibot, S. Soluble Trem-like Transcript-1 Regulates Leukocyte Activation andControls Microbial Sepsis.  J Immunol.  188(11):5585-92.  (2012) PMID: 22551551.  PMCID: In Process.
  1. Inyushin M.Y., Huertas, A., Kucheryavykh, Y., Kucheryavykh, L, Tsydzik, V., Sanabria, P., Eaton, M., Skatchkov, S., Rojas, L., Wessinger, W. L-DOPA Uptake in Astrocytic Endfeet Enwrapping Blood Vessels in Rat Brain.  Parkinson’s Dis. 2012;2012:321406 (2012). PMID: 22888467.  PMCID: 3409556 *
  1. Jorquera, R., Huntwork, S., Akbergenova, Y., Cho, R., Litteleton, J. Complexin Controls Spontaneous and Evoked Neurotransmitter Release by Regulating the Timing and Properties of Synaptotagmin Activity.  Neurosci. (2012) 12;32(50):18234-45.  PMID: 23238737. PMCID: 3530744.
  1. Koeing S., Rodríguez, L., Bartholomew, C., Carmichael, T., Barrow, G., Cabié, A., Hunter, R., Vázquez, G., Quava, A., Adomakoh, N., Figueroa, P., Liautaud, B., Torres, M., Pape, J. Long-Term Antiretroviral Treatment Outcomes in Seven Countries in the Caribbean.  AIDS 1;59(4):e60-e71 (2012).  PMID: 22240464.    PMCID: 3299899 *
  1. Kucheryavykh, L., Kucheryavykh, Y., Rolón, K., Skatchkov, S., Eaton, M., Cubano, L., Inyushin, M. Visualization of Implanted GL261 Glioma Cells in Mouse Brain Slices Using Fluorescent 4-(4-(dimethylamino)-styryl)-N-Menthylpyridinium Ioidide (ASP+).  53(5):305-309. Doi: 10.2144/000113940.  (2012) PMID: 23570046.  PMCID: 3667395 *
  1. Kurapati, K., Samikkannu, T., Kadiyala, D., Zainulabedin, S., Gandhi, N., Sathave, S., Indap, M., Boukli, N., Rodríguez, J.W., Nair, M. Combinatorial Cytotoxic Effects of Curcuma Longa and Zingiber Officinale on the PC-3M Prostate Cancer Cell Line.  J Basic Clin Physiol Pharmacol 23(4):139-46 (2012) PMID: 23072849.
  1. Long, R., Hui, C., Jagota, A., Bykhovskaia, M. Adhesion Energy can Regulate Vesicle Fusion and Stabilize Partially Fused States.  Royal Society Interface.  Epub Ahead of Print. (2012). PMID: 22258550  PMCID: 3367824
  1. Longas, M., Kotapati, A, Prasad, K, Banerjee, A., Santiago, J., Baksi, K., Banerjee, D. Balancing Life with Glycoconjugates:  Monitoring Unfolded Protein Response-Mediated Anti-angiogenic Action of Tunicamycin by Raman Spectroscopy.  Pure and Appl. Chem. 1;84(9):1907-18.  (2012) PMID: 22936838 PMCID: 3428797.*
  1. Martins, A., Alves, J., Pérez, D., Carrasco, M., Torres, W., Eterovic, V., Ferchmin, P., Ulrich, H. Kinin-B2 Receptor Mediated Neuroprotection after NMDA Excitotoxicity is Reversed in the Presence of Kinin-B1 Receptor Agonists.  Published online PLoS One v.7(2): e30755. (2012) PMID: 22348022 PMCID: 3277507. *
  1. Mazzio, E., Boukli, N., Rivera, N., Soliman, K. Pericellular pH Homeostasis is a Primary function of the Warburg Effect:  Inversion of Metabolic Systems to Control Lactate Steady State in Tumor Cells.  Cancer Sci.  103(3):422:32.  (2012) PMID:    PMCID:  3294166. *
  1. Mayor, A., Ruiz, Y., Fernández, D., Hunter, R. Neoplasm in HIV/AIDS Adult Population, Before and After Highly Active Antiretroviral Theraphy, In: Immunosupression.  .  ISBN 978-953-51-0152-9. (2012)  Book*
  1. Montalvo-Ortiz, B.L., Castillo-Pichardo, L., Hernández, E., Humphries-Bickley, T., De la Mota-Peynado, A., Cubano, L.A., Vlaar, C.P., Dharmawardhane, S. Characterization of EHop-016, Novel Small Molecule Inhibitor of Rac GTPase. J Biol Chem. 13;287(16):13228-38. (2012)  PMID: 22383527  PMCID: 3339933. *
  1. Powell, M., Boukli, N., Almeida, I., Perry, T., Dye, T., Pratap, S. Creation of a Proteomics and Informatics Collaborative Group to enhance Biomedical Research at Ethnically Diverse Institutions.  J Biomol Tech. v.23(Suppl) (2012).  PMID:  PMCID: 3630554. *
  1. Reyes, J., Negrón, J., Colón, H., Padilla, A., Millán, M., Matos, T., Robles, R. The Emerging of Xylazine as a new Drug of Abuse and its Health Consequences among Drug Users in Puerto Rico.  Urban Health. 89(3):519-526 (2012). PMID: 22391983  PMCID: 3368046
  1. Rodríguez, R., Ford, G., Xu, Z., Kraiselburd, E., Martínez, M., Eterovic, V., Colón, E., Rodríguez, I., Portilla, P., Ferchmin, P., Gierbolini, L., Rodríguez, M., Powell, M., Pulliam, J., McCraw, C., Gates, A., Ford, B. Acute Neuronal Injury and Blood Genomic Profiles in a Non-Human Primate Model for Ischemic Stroke.  Journal of Comparative Medicine.  62(5):427-38  (2012) PMID: 23114047  PMCID: 3472608.
  1. Ruiz-Candelaria, Y., Miranda, C., Hunter‑Mellado, R. F. KRAS Mutation Profile in Puerto Rican Patients with Colorectal Cancer:  Trends in Expression of KRAS Mutation in PR between April 2009 to January 2011. www.asco.org and www.jco.org (available May 16, 2012)  (2012) e14102. (Book)*
  1. Salgado, I., Serrano, M., García, J., Martínez, N., Maldonado, H., Báez, C., Lasalde, J., Silva W. SorLA in Glia:  Shared Subcellular Distribution Patterns with Caveolin-1.  Cell Mol Neurbiol. (2012)  PMID: 22127416. NIHMSID: 344677.
  1. Sepúlveda L., De la Rosa, A., Cumba, L., Boukli, N., Ríos-Olivares, E., Cubano, L. Prevalence of Drug Resistance and Associated Mutations in a Population of HIV-1+ Puerto Ricans: 2006-2010.  AIDS Research and Treatment.  Volume 2012, Article ID 934041, doi:10.1155/2012/934041. (2012) PMID: 22593823  PMCID: 3347695*
  1. Stevens, R., Akbergenova, Y., Jorquera, R., Littleton, J. Abnormal Synaptic Vesicle Biogenesis in Drosophilia Synaptogyrin Mutants.  Neurosci.  12;32(50):18054-67. (2012) PMID: 23238721.  PMCID: 3530745.



  1. Banerjee, A., Lang J., Hung, M., Sengupta, K., Banerjee, S.K., Baksi, K., Banerjee, D. Unfolded Protein Response is Required in nu/nu Mice Microvasculature for Treating Breast Tumor with Tunicamycin.  J Biol Chem. 19;286(33):29127-38 (2011) PMID: 21676868  PMCID: 3190720.*
  1. Banerjee, D.K., Oliveira, C.M., Tavárez, J.J., Katiyar, V.N., Saha, S., Martínez, J.A., Banerjee, A., Sánchez, a., and Baksi, K. Importance of a Factor VIIIc-like Glycoprotein Expressed in Capillary Endothelial Cells (eFactor VIIIc) in Angiogenesis. Adv Exp Med Biol. 705:453-464. (2011) PMID:  21618124.*
  1. Boukli, N., Delgado, B., Ricaurte, M., Espino, A. Fasciola Hepatica and Schistosoma Mansoni:  Identification of Common Proteins by Comparative Proteomic Analysis. J Parasitol. 97(5) 852-861(2011) Mar 11. PMID:  21506812.  PMCID: 3564592.*
  1. Bykhovskaia, M. Synapsin Regulation of Vesicle Organization and Functional Pools.  Semin Cell Dev Biol. 22(4):367:92.  (2011).  PMID:21827866.
  1. Eterovic, V., Pérez, D., Martins, A.H., Cuadrado, B., Carrasco, M., Ferchmin, P. A Cembranoid Protects Acute Hippocampal Slices Against Paraoxon Neurotoxicity.  Toxicology in Vitro. 25(7):1468-74.  (2011).  PMID: 21569834  PMCID:  3162106*
  1. Fernández, D., Figueroa, W., Miranda, C., Maysonet, J., Mayor, A., Hunter, R. Prevention Strategies for HIV Infection Risk Reduction among Hispanic/Latino Adolescents.  HIV Infection.  Chapter Number 4.  (2011) ISBN: 979-953-307-190-8.* (Book Chapter)
  1. Goodkin, K., Fernández, F., Forstein, M., Miller, E.N., Becker, J.T., Douaihy, A., Cubano, L., Santos, F.H., Filho, N.S., Zirulnik, J., Singh, D. A perspective on the proposal for neurocognitive disorder criteria in DSM-5 as applied to HIV-associated neurocognitive disorders. Neuropsychiatry (London). 2011 Oct 1; 1(5):431-440.  PMID: 22844348
  1. Kang, S., Deren, S., Colón, H. Differential Gender Effects of Depression on use of HIV Medications among HIV-Positive Puerto Rican drug Users. AIDS Care. 23(11):1467-71.  (2011).  PMID: 22022852
  1. Livney, M., Clark, C., Kariawish, J., Cartmeli, S., Negrón, M., Nuñez, J., Xie, S., Entenza-Cabrera, F., Vega, I., Arnold, S. Ethonoracial Differences in the Clinical Characteristics of Alzheimer’s Disease at Initial Presentation at an Urban Alzheimer’s Disease Center.i  Am J Geriatric Pesychiatry.  19(5):430-9. (2011) PMID: 21522051. PMID:
  1. Martínez-Montemayor, M., Rosario, R., Otero, E., Cubano, L., Dharmawardhane, S. Ganoderma Lucidum (Reishi) Inhibits Cancer Cell Growth and Expression of Key Molecules in Inflammatory Breast Cancer.  Nutrition and Cancer. Oct;63(7):1085-94. Epub Sep 2. 05:34  (2011). PMID:  PMCID: 3201987. NIHMSID:  NIHMS330291. *
  1. Mayor, A., Fernández, D., Dworkin, M., Ríos-Olivares, E., Hunter-Mellado, R. Toxoplasmic Encephalitis in an AIDS Cohort at Puerto Rico before and after HAART.  Am J Trop Med Hyg. 84(5):838-41. (2011).  PMID: 21540399, PMCID: 3083757 *
  1. Mayor, A., Ruiz, Y., Fernández, D., Hunter, R. HIV/AIDS Associated Malignant Disorders:  Role of Highly Active Antiretroviral Therapy.    (2011). ISBN:  978-953-308-19-8.  DOI: 10.5772/28075 (Book) *
  1. Nieves-Plaza, M., Ortiz, A., Colón, M., Molina, J., Castro, L., Rodríguez, V., Mayor, A., Vilá, L. Outcome and predictors of kidney disease progression in puerto ricans withSystemic Lupus Erythematosus Initially Presenting with mild Renal Involvement.  J Clin Rheumatol.  17(4):179-84. (2011) PMID: 21617555  PMCID: 3569025.*
  1. Rao, K., Boukli, N., Samikkannu, T., Cubano, L., Dakshayani, K, Nair, M. Proteomic Profiling in PC-3M Prostate Cancer Cell Line and Cytotoxic Effects of Cucurma Longa.  The Open Proteomics Journal. Vol. (4):1-11 (2011 is an open access journal, meaning that the full-text of all published articles is made freely available on the journal’s website with no subscription or registration barriers.*
  1. Reyes, J., Robles, R., Colón, H., Negron, J., Matos, T., Calderón, J. Polydrug use and Attempted Suicide among hispanic Adolescents in Puerto Rico.  Arch Suicide Res. 15(2):151-159. (2011)  PMID:
  1. Seidel, K., Derst, Ch., Salzmann, M., Holtje, M., Priller, J., Markgraf, R., Heinemann, S., Heilmann, H., Skatchkov, S., Eaton, M., Veh, R., and Pruss, H.  Expression of the Voltage-and Ca2+-dependent BK Potassium Channel Subunits BKβ1 and BKβ4 in Rodent Astrocytes.  Glia 59:893-902.  (2011). PMID: 21438011.