Wanda Vélez

Associate Professor
Ph.D., 1998; Tufts University, Boston, MA
ORCID #0000-0001-5310-1209
Academic Department(s)
Research Area
Research Interest
Neuroinflammation and the alpha 7 acetylcholine receptor

Dr. Vélez is studying the mechanisms for the reduction in pro-inflammatory cytokine levels after treatment with a natural compound found in tobacco called 4R cembranoid. This compound has been shown to allosterically modulate the alpha 7 nicotinic receptor. The alpha 7 receptor is a homopentameric membrane receptor found in neuronal and non-neuronal cells such as macrophages. During inflammation, activation of the alpha 7 receptor helps maintain balance between the pro- and anti-inflammatory cytokines.

Contact Information
Universidad Central del Caribe
P.O. Box 60327
Bayamón, PR 00960-6032
Tel.: (787) 798-3001 x 2036
e-mail: wanda.velez@uccaribe.edu