José W. Rodríguez

Associate Professor
Ph.D. 1998, Morehouse School of Medicine

Academic Department(s)
Microbiology and Immunology

Research Area
Cellular and Molecular Immunology

Research Interest
Immunopathologic mechanisms of chronic diseases
Immunological biomarkers for diagnosis, monitoring, and treatment of chronic diseases
Immunotherapeutic approaches for the prevention and treatment of chronic diseases

Selected Publications
Synthesis of novel C5-curcuminoid-fatty acid conjugates and mechanistic investigation of their anticancer activity. Sanabria-Rios DJ, Rivera-Torres Y, Rosario J, Rios C, Gutierrez R, Carballeira NM, Velez C, Zayas B, Alvarez-Colon F, Ortiz-Soto G, Serrano V, Altieri-Rivera J, Rios-Olivares E, Rodriguez JW.  Bioorg Med Chem Lett. 2015 May 15;25(10):2174-80. PMID: 25881826 PMCID: 4446575
Opiate addiction therapies and HIV-1 Tat: interactive effects on glial [Ca2+]i, oxyradical and neuroinflammatory chemokine production and correlative neurotoxicity. Fitting S, Zou S, El-Hage N, Suzuki M, Paris JJ, Schier CJ, Rodríguez JW, Rodríguez M, Knapp PE, Hauser KF.  Curr HIV Res. 2015 Mar 11. PMID: 25760046.
Paraoxon and Pyridostigmine Interfere with Neural Stem Cell Differentiation. Berrios VO, Boukli NM, Rodríguez JW, Negraes PD, Schwindt TT, Trujillo CA, Oliveira SL, Cubano LA, Ferchmin PA, Eterovic VA, Ulrich H, Martins AH.  Neurochem Res. 2015 Mar 11. PMID: 25758980
Antibacterial Activity of 2-Alkynoic Fatty Acids Against Multidrug-Resistant Bacteria. Sanabria-Rios DJ, Rivera-Torres Y, Maldonado-Dominguez G, Domínguez I, Ríos C, Díaz D, Rodríguez JW, Altieri-Rivera JS, Ríos-Olivares E, Cintrón G, Montano N, Caballeira N.   Chem Phys. Lipids. 2014 Feb;178:84-91.  
Combinatorial cytotoxic effects of Curcuma longa and Zingiber officinale on the PC-3M prostate cancer cell line. Kurapati KR, Samikkannu T, Kadiyala DB, Zainulabedin SM, Gandhi N, Sathaye SS, Indap MA, Boukli N, Rodriguez JW, Nair MP. J Basic Clin Physiol Pharmacol. 2012 Oct 12;0(0):1-8. 

Implications of ER stress, the unfolded protein response, and pro- and anti-apoptotic protein fingerprints in human monocyte-derived dendritic cells treated with alcohol. Boukli NM, Saiyed ZM, Ricaurte M, Rodriguez JW, Ríos Olivares E, Cubano LA, Nair MP. Alcohol Clin Exp Res. 2010 Dec;34(12):2081-8.

Contact Information
Universidad Central del Caribe
P.O. Box 60327
Bayamón, PR 00960-6032

Tel  (787) 798-3001 ext. 2084