Pedro Ferchmin

Ph.D. 1971, National Uni. of Cordoba, Argentina

Academic Department(s)
Department of Biochemistry

Research Area
Neuroscience-Neuroprotection against delayed neurodegeneration

Research Interest
The study of the neuroprotective effect of cembranoids against the delayed neurodegeneration caused by organophosphorous (OP).

Selected Publications
γ-Aminobutyric acid type a receptor inhibition triggers a nicotinic neuroprotective mechanism. Ferchmin PA, Pérez D, Castro Alvarez W, Penzo MA, Maldonado HM, Eterovic VA.  J Neurosci Res. 2013 Mar;91(3):416-25. 
Acute neuronal injury and blood genomic profiles in a nonhuman primate model for ischemic stroke. Rodriguez-Mercado R, Ford GD, Xu Z, Kraiselburd EN, Martinez MI, Eterović VA, Colon E, Rodriguez IV, Portilla P, Ferchmin PA, Gierbolini L, Rodriguez-Carrasquillo M, Powell MD, Pulliam JV, McCraw CO, Gates A, Ford BD. Comp Med. 2012 Oct;62(5):427-38. 
Kinin-B2 receptor mediated neuroprotection after NMDA excitotoxicity is reversed in the presence of kinin-B1 receptor agonists. Martins AH, Alves JM, Perez D, Carrasco M, Torres-Rivera W, Eterović VA, Ferchmin PA, Ulrich H. PLoS One. 2012;7(2):e30755.
 A cembranoid protects acute hippocampal slices against paraoxon neurotoxicity.  Eterović VA, Pérez D, Martins AH, Cuadrado BL, Carrasco M, Ferchmin PA. Toxicol In Vitro. 2011 Oct;25(7):1468-74. doi: 10.1016/j.tiv.2011.04.021. Epub 2011 May 4. Erratum in: Toxicol In Vitro. 2011 Dec;25(8):2152.
Actions of octocoral and tobacco cembranoids on nicotinic receptors. Ferchmin PA, Pagán OR, Ulrich H, Szeto AC, Hann RM, Eterović VA. Toxicon. 2009 Dec 15;54(8):1174-82. doi: 10.1016/j.toxicon.2009.02.033.
Contact Information
Universidad Central del Caribe
P.O. Box 60327
Bayamón, PR 00960-6032

Tel  (787) 798-3001 ext. 2033