Suranganie Dharmawardhane

Adjunct Associate Professor
Ph.D. 1987, University of Massachusetts, Amherst, MA

Academic Department(s)
Anatomy and Cell Biology

Research Area
Cell and Molecular Biology

Research Interest
Resveratrol in breast cancer cell survival or apoptosis
Role of soy phytoestrogens in breast cancer progression

Selected Publications
Dietary grape polyphenol resveratrol increases mammary tumor growth and metastasis in immunocompromised mice. Castillo-Pichardo L, Cubano LA, Dharmawardhane S. BMC Complement Altern Med. 2013 Jan 8;13:6
The soy isoflavone equol may increase cancer malignancy via up-regulation of eukaryotic protein synthesis initiation factor eIF4G. de la Parra C, Otero-Franqui E, Martinez-Montemayor M, Dharmawardhane S. J Biol Chem. 2012 Dec 7;287(50):41640-50.
Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer. Castillo-Pichardo L, Dharmawardhane SF. Nutr Cancer. 2012;64(7):1058-69.
Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase. Montalvo-Ortiz BL, Castillo-Pichardo L, Hernández E, Humphries-Bickley T, De la Mota-Peynado A, Cubano LA, Vlaar CP, Dharmawardhane S. J Biol Chem. 2012 Apr 13;287(16):13228-38.
Ganoderma lucidum (Reishi) inhibits cancer cell growth and expression of key molecules in inflammatory breast cancer. Martínez-Montemayor MM, Acevedo RR, Otero-Franqui E, Cubano LA, Dharmawardhane SF. Nutr Cancer. 2011;63(7):1085-94.

Contact Information
Universidad Central del Caribe
P.O. Box 60327
Bayamón, PR 00960-6032

Tel:  (787) 798-3001 ext. 2152