Gabriela Ortiz

ORCID #0000-0003-2037-5881   Gabriela Ortiz
B.S., University of Puerto Rico at Cayey
 
Academic Program
Ph.D. Cell and Molecular Biology
 
Department
Biochemistry
 
Publications
Acevedo-Diaz A, Ortiz-Soto G, Suarez-Arroyo IJ, Zayas-Santiago A, Martinez-Montemayor MM. Ganoderma lucidumExtract Reduces the Motility of Breast Cancer Cells Mediated by the RAC Lamellipodin Axis.  2019 may 19;11(5).  PMID: 31109134
 
Martínez-Montemayor MM, Ling T, Suárez-Arroyo IJ, Ortiz-Soto G,Santiago-Negrón CL, Lacourt-Ventura MY, Valentín-Acevedo A, Lang WH, Rivas F. Identification of Biologically Active Ganoderma lucidum Compounds and Synthesis of Improved Derivatives That Confer Anti-cancer Activities in vitro.  Pharmacol. 2019 Feb 19;10:115. PMID: 30837881 PMCID: 6389703
 
Rios-Fuller TJ, Ortiz-Soto G,Lacourt-Ventura M, Maldonado-Martinez G, Cubano LA, Schneider RJ, Martinez-Montemayor MM. Ganoderma lucidum extract(GLE) impairs breast cáncer stem cells by targeting the STAT3 pathway. Oncotarget. 2018 Nov 13;9(89):35907-35921.  PMID: 30542507  PMCID: 626759

Sanabria-Rios DJ, Rivera-Torres Y, Rosario J, Gutierrez R, Torres-Garcia Y, Montano N, Ortiz-Soto G, Rios-Olivares E, Rodríguez JW, Carballeira NM. Chemical conjugation of 2-hexadecynoic acid to C5-curcumin enhances its antibacterial activity against multi-drug resistant bacteria. Bioorg Med Chem Lett. 2015 Nov 15;(22):5067-71. PMID: 26483137 PMCID:4663078

Moreira LG, Orellano EA, Rosado K, Guido RV, Andricopulo AD, Ortiz-Soto GO, Rodríguez JW, Sanabria-Ríos DJ, Carballeira NM.  The (5Z)-5-Pentacosenoic and 5-Pentacosynoic Acids Inhibit the HIV-1 Reverse Transcriptase.  Lipids. 2015 Oct;50(10):1043-50.  PMID: 26346647

Sanabria-Rios DJ, Rivera-Torres Y, Rosario J, Rios C, Gutierrez R, Carballeira NM, Velez C, Zayas B, Alvarez-Colon F, Ortiz-Soto G, Serrano V, Altieri-Rivera J, Rios-Olivares E, Rodriguez JW. Synthesis of novel C5-curcuminoid-fatty acid conjugates and mechanistic investigation of their anticancer activity. Bioorg Med Chem Lett. 2015 May 15;25(10):2174-80. PMID: 25881826 PMCID: 4446575

 
Presentations
Ortiz-Soto G, Suárez-Arroyo IJ, Martínez-Montemayor MM.Role of Metadherin in correlation with NF-kB in Inflammatory Breast Cancer.  ASCB 2018 Annual Meeting. San Diego, CA (December 2018)
 
Ortiz-Soto G,Acevedo-Díaz AC, Suárez-Arroyo I, Zayas-Santiago A, Martínez-Montemayor MM. Ganoderma lucidum extract decreases motility and lamellipodia formation of triple-negative metastatic breast cancer.  1stUCC Biomedical and Clinical Student and Resident Research Symposium: Breaking Barriers. Bayamón, PR (November 2018)
 
Ortiz-Soto G, Acevedo-Díaz A, Rios-Fuller TJ, Suárez-Arroyo IJ, Martínez-Montemayor MM. Ganoderma lucidum extract decreases cell migration and invasion in triple-negative metastatic breast cancer.2018 PRCTRC Scientific Day. San Juan, PR (May 2018)
 
Ortiz-Soto G,Suárez-Arroyo IJ, Martínez-Montemayor MM.The functional role of Metadherin in inflammatory Breast Cancer Progresssion.  3rdPuerto Rico Cancer Research Meeting. San Juan, PR (May 2018)
 
Ortiz-Soto G,Santiago-Negrón CL, Suarez-Arroyo I, Ling T, Rivas F, Martínez-Montemayor MM. Ganoderma lucidumderivative fraction effects in triple-negative breast cancer.  2017 ASCB Annual Meeting. Philadelphia, CA (December 2017)
 
Ortiz-Soto G, Acevedo-Díaz A, Rios-Fuller TJ, Loperena-Álvarez Y. Inhibitory Effects of Ganoderma lucidum extract (GLE) in tripe-negative metastatic breast cancer migration and protein expression.  Emory University STEM Research and Career Symposium. Atlanta, GA (October 2017)
 
Ortiz-Soto G, Acevedo-Díaz A, Rios-Fuller TJ, Loperena-Álvarez Y, Cubano LA, Martínez-Montemayor MM. of Ganoderma lucidum extract (GLE) in tripe-negative metastatic breast cancer migration and protein expression. 2016 ASCB Annual Meeting. San Francisco, CA (December 2016)
 

Awards
December 2018
Second Place – Poster Competition
ASCB Annual Meeting

November 2018
PR INBRE Graduate Junior Research Associates

December 2017
ASCB Minority Affairs Committee Travel Award – 2017 ASCB Annual Meeting

June 2017
Emory STEM Symposium Travel Award – Emory University-Laney Graduate School STEM Research and Career Symposium

September 2016
MAC Travel Award – 2016 ASCB Annual Meeting